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Tirzepatide is an innovative pharmacological agent that represents a significant advancement in the treatment of type 2 diabetes mellitus (T2DM) and obesit. This drug is a dual agonist that targets both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. These incretin hormones are naturally occurring peptides involved in the regulation of glucose homeostasis and energy balance. By simultaneously targeting these pathways, tirzepatide exerts a synergistic effect that enhances its efficacy in managing hyperglycemia and promoting weight loss, distinguishing it from existing therapies that typically target only the GLP-1 receptor.
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