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S23 is undoubtedly one of the strongest SARMs in development at the moment. S23 was created by modifying the structure of an older and less effective SARM called C-6 by replacing the para-nitro group of C-6 with a cyano group. Pharmacokinetic studies have shown that C-6 is 76%bioavailable when taken orally, and when the para-nitro group is replaced with a cyano group, S23 is able to achieve 96% bioavailability when taken orally.
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